Purpose :
@EN We analysed 99mTc-MAG3 renal scans to evaluate renal function of transplanted kidney and to detect various renal transplant complications, measuring the ration of renal radioactivity at three minutes to that at 20 minutes(elimination index).
@ES Material and Methods :
@EN The fifty seven renal transplantation recipients were studied. There were 50 normal functioning transplanted kidneys as group I and 7 abnormal functioning transplanted kidney, including 5 cases of acute renal rejection, 2 cases of acute
tubular
necrosis as group II. The protocol consisted of : (1) 99mTc-MAG3 740MBq injection intravenously; (2) sequential imaging for 2min(60two-second images) followed by 30min(30 sixty-second images); (3) drawing of region of interest(ROI) on renal
imaging; (4)
time activity curves were generated from renal ROI after background subtraction, and time of maximum activity(Tmax) and half time of maximal peak radioactivity(T1/2) were produced in the renogram curve. (5) EI through Bischof-Delaloye method as
determined on the renogram curve.
@ES Results :
@EN Normal group( I ) shows mean EI of 2.21(95.0% Confidence limit of 2.01-2.87), Tmax of 154 sec, t1/2 of 1,139 sec. Abnormal group(II) shows mean EI of 0.74, Tmax of 1,466 sec, t1/2 of 19.224 sec. The EI, Tmax, T1/2, BUN and serum creatinine
values
are significantly different between normal group( I ) and abnormal group(II)(p<0.0001).
@ES Conclusion :
@EN By measuring EI with 99mTc-MAG3, renal function of transplanted kidney could be easily evaluated and various complications could be detected early.
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